Enfermedades reumáticas y alergias, la dualidad del sistema inmunológico

Autores/as

  • Gabriela Athziri Sánchez-Zuno Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Instituto de Investigación de Ciencias Biomédicas, Jalisco https://orcid.org/0000-0002-4390-8604
  • Edith Oregón-Romero Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Instituto de Investigación de Ciencias Biomédicas, Jalisco https://orcid.org/0000-0001-6010-0837
  • Jorge Hernández-Bello Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Instituto de Investigación de Ciencias Biomédicas, Jalisco https://orcid.org/0000-0001-8004-1811
  • Guillermo González-Estevez Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Instituto de Investigación de Ciencias Biomédicas, Jalisco https://orcid.org/0000-0002-0244-6298
  • Rodrigo Vargas-Rosales Universidad de San Carlos de Guatemala, Facultad de Ciencias Médicas, Escuela de Estudios de Posgrado, Guatemala https://orcid.org/0000-0002-9042-0839
  • José Francisco Muñoz-Valle Universidad de Guadalajara, Centro Universitario de Ciencias de la Salud, Instituto de Investigación de Ciencias Biomédicas, Jalisco https://orcid.org/0000-0002-2272-9260

DOI:

https://doi.org/10.29262/ram.v68i4.984

Palabras clave:

Alergias, Enfermedades reumáticas, Autoinmunidad, Hipersensibilidad, Lupus eritematoso sistémico, Síndrome de Sjogren, Artritis reumatoide

Resumen

Las enfermedades reumáticas autoinmunes son trastornos multisistémicos que afectan principalmente las articulaciones y los músculos; algunos ejemplos de estas afecciones son la artritis reumatoide, el lupus eritematoso sistémico y el síndrome de Sjögren. En general, las enfermedades reumáticas autoinmunes tienen una alta prevalencia en todo el mundo y son altamente incapacitantes para quienes las padecen. Una de las principales limitaciones en la actualidad para el manejo de estas enfermedades es que su factor desencadenante sigue siendo desconocido en la mayoría de los casos y el conocimiento de los factores asociados con su exacerbación es limitado. En esta revisión se explorará la posible relación de las alergias como desencadenante de enfermedades reumáticas autoinmunes. También analizaremos los aspectos básicos y generales de ambas enfermedades y el desarrollo de procesos alérgicos y reacciones de hipersensibilidad a los fármacos utilizados en el tratamiento de enfermedades reumáticas.

Citas

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Publicado

2021-12-07

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