Abstract
Background: The association of asthma with COVID-19 remains controversial. Objective: to establish the prevalence of asthma in a sample of patients with COVID-19 associated pneumonia; in addition, to describe the clinical characteristics of patients with asthma compared with patients without asthma.
Methods: Clinical data corresponding to 120 patients hospitalized for pneumonia associated with SARS-CoV-2 infection were analyzed. Patients with and without asthma were compared based on the severity of COVID-19.
Results: The prevalence of asthma in patients with COVID-19 pneumonia was 3.5% (95% CI: 1.5% to 9.6%). When comparing the severity of COVID-19 between patients with asthma and patients without asthma, it did not differ according to symptoms, comorbidity, duration of symptoms, need for mechanical ventilation, biomarkers of inflammation and the occurrence of death. Patients with asthma and COVID-19 showed a high T2 phenotype, with poor respiratory function and no use of regular treatment for asthma control.
Conclusions: No significant differences in the frequency of assisted mechanical ventilation or death were observed between patients hospitalized for COVID-19-associated pneumonia with and without a history of asthma.
Keywords: asthma; COVID-19; prevalence; SARS-CoV-2.
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