Keywords
exanthema
dermatitis herpetiformis
How to Cite
Plaudit
Abstract
Introduction:
Short-lasting erythematous-papular skin rashes suggest a clinical diagnosis of urticaria. However, it may be another type of dermatitis whose diagnosis may require complementary examinations.
Case report: 53-year-old woman diagnosed in 2016 with diffuse large B-cell lymphoma in complete remission. Since 2010 she presented daily episodes of erythematous-papular lesions lasting 24-36 hours. She was treated with antihistamines, oral corticosteroids and Omalizumab without control.
A study was carried out consisting of:
Blood tests: haemogram, serum immunoglobulins, thyroid hormones, complement, cryoglobulins, proteinogram, autoimmunity markers. Of note: positive ANA 1/320 mitotic nuclear pattern.
Skin biopsy (x2) compatible with dermatitis herpetiformis.
Celiac disease antibodies and HLA DQA1 and DQB1 locus. HLA-DQ2 positive DQ2.5 in heterozygosis.
Discussion: Dermatitis herpetiformis was diagnosed and a gluten-free diet and dapsone were indicated with good control, highlighting the importance of differential diagnosis of papular exanthema.
References
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