Abstract
Background: Prevalence of latex allergy in medical students is not known.
Objective: To determine the prevalence of self-reported latex allergy and associated factors in medical students.
Methods: Cross-sectional, analytical study of students with or without self-reported latex allergy. By means of a structured questionnaire, past personal and family history of allergic disease, time and frequency of exposure to latex gloves and symptoms after exposure to products or foods associated with latex allergy were inquired. Logistic regression models were carried out.
Results: Out of 854 subjects, 431 (50.5%) were females. Median age was 21 years. Overall prevalence of latex allergy was 4.3% (95% CI = 3.1 to 5.9). Associated risk factors were age (OR = 1.37; 95% CI = 1.05 to 1.79), personal history of atopic dermatitis (OR = 7.32; 95% CI = 3.14 to 17.08), use of gloves ≥ 15/week (OR = 2.59; 95% CI = 1.17 to 5.76), use of latex products (OR = 5.76; 95% CI = 2.15 to 15.49) and fruit allergy (OR = 3.24; 95% CI = 1.27 t o8.27).
Conclusion: Four out of a hundred students reported latex allergy. Age, personal history of atopic dermatitis, higher frequency of exposure to latex gloves and history of fruit allergy were risk factors for self-report latex allergy.
References
Bousquet J, Flahault A, Vandenplas O, Ameille J, Duron JJ, Pecquet C, et al. Natural rubber latex allergy among health care workers: A systematic review of the evidence. J Allergy Clin Immunol. 2006;118(2):447-454. DOI: 10.1016/j.jaci.2006.03.048
Grzybowski M, Ownby DR, Peyser PA, Johnson CC, Schork MA. The prevalence of anti-latex IgE antibodies among registered nurses. J Allergy Clin Immunol. 1996;98(3):535-544. DOI: 10.1016/S0091-6749(96)70087-8
Brown RH, Schauble JF, Hamilton RG. Prevalence of latex allergy among anesthesiologist: Identification of sensitized but asymptomatic individuals. Anesthesiology. 1998;89(2):292-299. DOI: 10.1097/00000542-199808000-00004
Guzmán MA, Arancibia V, Salinas J, Rodas C, Roa J, Villegas R. Prevalence of latex hypersensitivity in operating room workers of the University of Chile Clinical Hospital. Rev Med Chil. 2005;133(5):535-540. DOI: S0034-98872005000500004
Gholizadeh N, Khoeini-Poorfar H, Mehdipour M, Johari M, Rashidi Y, Jabbari-Khamnei H. Prevalence of allergy to latex gloves among dental practitioners and its association with other materials. Avicenna J Dent Res. 2011;3(1):37-42.
Amarasekera M, Rathnamalala N, Samaraweera S, Jinadasa M. Prevalence of latex allergy among healthcare workers. Int J Occup Med Environ Health. 2010;23(4):391-396. DOI: 10.2478/v10001-010-0040-5
Yusoff A, Murray SA, Rahman NA, John J, Mohammad D, Tin-Oo MM. Self-reported latex glove allergy among dental personnel in Kelantan State, Malaysia. Int Med J. 1994;20(3):343-345.
Krasteva A, Stoeva I, Nikolov G, Petrunov B, Dimitrova S, Kisselova A. Latex sensitivity among dental students. OHDMBSC. 2008;7(1):31-34.
Vangveeravong M, Sirikul J, Daengsuwan T. Latex allergy in dental students: A cross-sectional study. J Med Assoc Thai. 2011;94(Suppl 3):S1-S8.
Tarlo SM, Sussman GL, Holness DL. Latex sensitivity in dental students and staff: A cross-sectional study. J Allergy Clin Immunol. 1997;99(3):396-401. DOI: 10.1016/S0091-6749(97)70058-7
Epling C, Duncan J, Archibong E, Østbye T, Pompeii LA, Dement J. Latex allergy symptoms among health care workers: Results from a university health and safety surveillance system. Int J Occup Environ Health. 2011;17(1):17-23. DOI: 10.1179/107735211799031176
Mathias LA, Botelho MP, Oliveira LM, Yamamura SJ, Bonfá RL, Marsura S. Prevalence of signs/symptoms suggestive of latex sensitization in health care workers. Rev Bras Anestesiol. 2006;56(2):137-146. DOI: 10.1590/S0034-70942006000200005
Buss ZS, Fröde TS. Latex allergen sensitization and risk factors due to glove use by health care workers at public health units in Florianopolis, Brazil. J Investig Allergol Clin Immunol. 2007;17(1):27-33. DOI: 10.1067/mai.2003.45
Bernardini R, Novembre E, Lombardi E, Pucci N, Monaco MG, Vierucci A, et al. Risk factor for latex allergy in 54 children with atopy and latex sensitization. J Allergy Clin Immunol. 2003;111(1):199-200. DOI: 10.1067/mai.2003.45
Chen YH, Lan JL. Latex allergy and latex-fruit syndrome among medical workers in Taiwan. J Formos Med Assoc. 2002;101(9):622-626. Disponible en: http://www.fma.org.tw/jfma/PDF/2002-101/Issue%2009/A3.pdf
Phaswana SM, Naidoo S. The prevalence of latex sensitisation and allergy and associated risk factors among healthcare workers using hypoallergenic latex gloves at King Edward VIII Hospital, KwaZulu-Natal South Africa: A cross-sectional study. BMJ Open. 2013;3(12):e002900. DOI: 10.1136/bmjopen-2013-002900
Liss GM, Sussman GL, Deal K, Brown S, Cividino M, Siu S, et al. Latex allergy: Epidemiological study of 1351 hospital workers. Occup Environ Med. 1997;54(5):335-342. DOI: 10.1136/oem.54.5.335
Verna N, Di-Giampaolo L, Renzetti A, Balatsinou L, Di-Stefano F, Di-Gioacchino G, et al. Prevalence and risk factors for latex-related diseases among healthcare workers in an Italian general hospital. Ann Clin Lab Sci. 2003;33(2):184-191.
Tang MB, Leow YH, Ng V, Koh D, Goh CL. Latex sensitisation in healthcare workers in Singapore. Ann Acad Med Singapore. 2005;34(5):376-382. Disponible en: https://pdfs.semanticscholar.org/b2e6/9c6c96a78c9d2ffd0bc46fb2dd3af5252b72.pdf
Moreno HL, Ávila E, Angulo Y, Portillo J, Moreno L, Reza G, et al. Frequency in allergy to proteins of latex in health care workers. Allergol Immunopathol (Madr). 2005;33(4):210-213. DOI: 10.1157/13077745
Pérez-Fort P, Jiménez-Saab NG, Sánchez-Hernández G, Durán-Salgado MB, Navarrete-Sánchez JI. Riesgo de hipersensibilidad al látex entre profesionistas del área de la salud. Med Int Mex. 2012;28(6):560-563. Disponible en: http://www.medigraphic.com/pdfs/medintmex/mim-2012/mim126f.pdf
Liss GM, Sussman GL. Latex sensitization: Occupational versus general population prevalence rates. Am J Ind Med. 1999;35(2):196-200. DOI: 10.1002/(SICI)1097-0274(199902)35:2<196::AID-AJIM12>3.0.CO;2-Y
De-Marchi F, Piacentini GL, Piazza M, Sandri M, Boner AL, Peroni DG. Correlation of skin barrier impairment in atopic dermatitis with aeroallergen sensitization. Allergy Asthma Proc. 2015;36(6):e127-e133. DOI: 10.2500/aap.2015.36.3872
Blanco C. Latex-fruit syndrome. Cur Allergy Asthma Rep. 2003;3(1):47-53.
Blanco C. Síndrome látex-frutas. Allergol Immunopathol (Madr). 2002;30(3):156-163. Disponible en: http://www.elsevier.es/es-revista-allergologia-et-immunopathologia-105-articulo-sindrome-latex-frutas-13029650

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright (c) 2018 Revista Alergia México