Supplementary Files
Keywords
Economic burden
Quality of life
Disease control
Abstract
Background: Chronic urticaria (CU) manifests itself with hives and sometimes angioedema. Physical and social discomfort worsens patient quality of life. CU has an important impact on patients’ economy.
Objective: To evaluate the relationship of quality of life (QoL) with economic burden and chronic urticaria control of in patients treated at our center.
Methods: Cross-sectional, descriptive, observational study. We included CU-diagnosed adult patients. The CU-Q2oL and UCT questionnaires in Spanish and the economic burden and comorbidities questionnaire developed by our center were applied. A sample size of 36 patients was calculated.
Results: 36 patients were included, out of which 58.3% were females. Mean age was 39.9 ± 15.6 years. Regarding QoL, 66.7% of patients reported being "A little" affected, 25% "Somewhat" and 8.3% "A lot", and its relationship with monthly income yielded a p-value of 0.017. 38.9% of patients reported having a monthly income of less than $ 5000 pesos. When disease control was compared with the CU-Q2oL, a significant difference was obtained for questions concerning itching.
Conclusion: There was association between the quality of life of patients with chronic urticaria and monthly income, the lower the income, the more will the quality of life be affected. Furthermore, greater CU control was observed to reduce the negative effects on quality of life caused by itching.
References
Larenas-Linnemann D, Medina-Ávalos MA, Ortega-Martell JA, Beirana AM, Rojo I, Morales-Sánchez MA, et al. Guía mexicana para el diagnóstico y el tratamiento de la urticaria. Rev Alerg Mex. 2014;61 Supl 2:S117-S193.
Kaplan AP. Chronic urticaria: Pathogenesis and treatment. J Allergy Clin Immunol 2004; 114(3):465-474. DOI: 10.1016/j.jaci.2004.02.049
Bernstein, Lang DM, Khan DA, Craig T, Dreyfus D, Hsieh F, et al. The diagnosis and management of acute and chronic urticaria: 2014 update. J Allergy Clin Immunol. 2014;133(5):1270-1277. DOI: 10.1016/j.jaci.2014.02.036
Weldon DR. Quality of life in patients with urticaria. Allergy Asthma Proc. 2006;27(2):96-99.
Fine LM, Bernstein JA. Guideline of chronic urticaria beyond. Allergy Asthma Immunol Res. 2016;8(5):396-403. DOI: 10.4168/aair.2016.8.5.396
Cariño-Cartagena D, Velasco-Medina A, Fernández de Córdova-Aguirre J, Arroyo-Cruz M, Velázquez-Samano G. Descriptive study of urticaria and angioedema in Allergy and Immunology Department of Hospital General de Mexico Dr. Eduardo Liceaga. Ann Allergy Asthma Immunol. 2013;111:349.
Saini SS. Chronic spontaneous urticaria etiology and pathogenesis. Immunol Allergy Clin North Am. 2014;34(1):33-52. DOI: 10.1016/j.iac.2013.09.012
Sánchez-Borges M, Asero R, Ansotegui IJ, Baiardini I, Bernstein JA, Canonica GW, et al. Diagnosis and treatment of urticaria and angioedema: a worldwide perspective. World Allergy Organ J. 2012;5(11):125-147. DOI: 10.1097/WOX.0b013e3182758d6c
Vietri J, Turner SJ, Tian H, Isherwood G, Balp MM, Gabriel S. Effect of chronic urticarial on US patients: analysis of the National Health and Wellnes Survey. Ann Allergy Asthma Immunol. 2015:115(4):306-311. DOI: 10.1016/j.anai.2015.06.030
Sanclemente G, Burgos C, Nova J, Hernández F, González C, Reyes MI, et al. The impact of skin diseases on quality of life: a multicenter study. Actas Dermosifiliogr. 2017;108(3):244-252. DOI: 10.1016/j.ad.2016.11.008
Gallardo-Martínez G, Arias-Cruz A, González-Díaz SN, Galindo-Rodríguez G. Costos derivados de la atención médica del asma en un grupo de niños del Noreste de México. Rev Alerg Mex. 2007;54(3):82-85.
Zazzali JL, Broder MS, Chang E, Chiu MW, Hogan DJ. Cost, utilization, and patterns of medication use associated with chronic idiopathic urticaria. Ann Allergy Asthma Immunol. 2012;108(2):98-102. DOI: 10.1016/j.anai.2011.10.018
Hernández-Ochoa C, Gómez-Gómez C, Rodríguez-Rodríguez I, Riquelme-Heras HM, De-La-Garza-Navarro RE, González-Díaz SN, et al. Prevalencia de urticaria crónica y patologías asociadas en el Centro Regional de Alergia e Inmunología Clínica del Hospital Universitario “Dr. José Eleuterio González”, Universidad de Nuevo León. Medicina Universitaria. 2013;15(60):114-117. Disponible en: http://www.elsevier.es/es-revista-medicina-universitaria-304-articulo-prevalencia-urticaria-cronica-patologias-asociadas-X1665579613496113
Valero A, Herdman M, Bartra J, Ferrer M, Jáuregui I, Dávila I, et al. Adaptation and validation of the Spanish version of the Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL). J Investig Allergol Clin Immunol. 2008;18(6):426-432.
Weller K, Groffik A, Church MK, Hawro T, Krause K, Metz M, et al. Development and validation of the Urticaria Control Test: A patient-reported outcome instrument for assessing urticaria control. J Allergy Clin Immunol. 2014;133(5):1365-1372. DOI: 10.1016/j.jaci.2013.12.1076
Dias-Coelho GA, Pires GV, Rodrigues-Do-Valle SO, Duarte-Dortas S, Levy S, Baiardini I, et al. Impact of chronic urticarial on the quality of life of patients followed up at a university hospital. An Bras Dermatol. 2016;91(6):754-759. DOI: 10.1590/abd1806-4841.20165071
Tincopa-Wong OW. Urticaria y angioedema: una visión general. Acta Med Per. 2014:31(2):111-124. Disponible en: http://www.scielo.org.pe/pdf/amp/v31n2/a08v31n2.pdf
Ferrer M. Epidemiology, healthcare, resources, use and clinical features of different types of urticaria. Alergológica 2005. J Investg Allergol Clin Immunol. 2009;19(Suppl 2):21-26.
Aguilar-Hinojosa NK, Segura-Méndez NH, Lugo-Reyes SO. Correlación de la gravedad de la urticaria crónica y calidad de vida. Rev Alerg Mex. 2012;59(4):180-186.
Gaig P, Olona M, Muñoz-Lejarazu D, Caballero MT, Domínguez FJ, Echechipia S, et al. Epidemiology of urticaria in Spain. J Investig Allergol Clin Immunol. 2004;14(3):214-220.
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