Abstract
Allergy to fruits and vegetables is the most common primary food allergy in Mediterranean countries, especially the lipid transfer proteins (LTPs) syndrome. This study is the first research that studies multiple clinical, allergological and therapeutics characteristics of allergies to plants in the South-East of Spain, and assessing whether these characteristics differ in emergency room or outpatient clinic. This is a prospective study of patients who consult for the first time for allergy to vegetables at Granada, Spain. We record demographic data, symptoms, allergological study and indicated therapy. The characteristics obtained agree with the current bibliographic except the higher prevalence than other areas of positive sensitization of Pru p 3, Cor a 9 and Ara h 9, which predisposes to severe allergic reactions. We conclude: Allergy to plant food in Granada is a more severe phenotype than other geographic areas from Spain, especially in young adults sensitized by different LTPs and pollinosis to olive pollen.
References
Tham EH, Leung DYM. How different parts of the world provide new insights into food allergy. Allergy Asthma Immunol Res. 2018;10(4):290-299. DOI: 10.4168/aair.2018.10.4.290
Skypala IJ, Cecchi L, Shamji MH, Scala E, Till S. Lipid transfer protein allergy in the United Kingdom: characterization and comparison with a matched Italian cohort. Allergy. 2019;74(7):1340-1351. DOI: 10.1111/all.13747
Carlson G, Coop C. Pollen food allergy syndrome (PFAS): a review of current available literature. Ann Allergy Asthma Immunol. 2019;123(4):359-365. DOI: 10.1016/j.anai.2019.07.022
Asero R, Piantanida M, Pinter E, Pravettoni V. The clinical relevance of lipid transfer protein. Clin Exp Allergy. 2018;48(1):6-12. DOI: 10.1111/cea.13053
Asero R, Piantanida M, Pravettoni V. Allergy to LTP: to eat or not to eat sensitizing foods? A follow-up study. Eur Ann Allergy Clin Immunol. 2018;50(4):156-162. DOI: 10.23822/EurAnnACI.1764-1489.57
Sánchez-López J, Gázquez V, Rubira N, Valdesoiro L, Guilarte M, Garcia-Moral A, et al. Food allergy in Catalonia: clinical manifestations and its association with airborne allergens. Allergol Immunopathol (Madr). 2017;45(1):48-54. DOI: 10.1016/j.aller.2016.06.004
Sociedad Española de Alergología e Inmunología Clínica [Internet]. Madrid: Alergológica 2015: factores epidemiológicos, clínicos y socioeconómicos de las enfermedades alérgicas en España. En: Alergol´gica 2015; 2017. Disponible en: https://www.seaic.org/inicio/noticias-general/alergologica-2015.html
Muñoz-Cano R, Pascal M, Araujo G, Goikoetxea MJ, Valero AL, Picado C, et al. Mechanisms, cofactors, and augmenting factors involved in anaphylaxis. Front Immunol. 2017;8:1193. DOI: 10.3389/fimmu.2017.01193
Rial MJ, Sastre J. Food allergies caused by allergenic lipid transfer proteins: what is behind the geographic restriction? Curr Allergy Asthma Rep. 2018;18(11):56. DOI: 10.1007/s11882-018-0810-x

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright (c) 2022 Revista Alergia México