Palabras clave
reacción por fármacos
exantema
eosinofilia
síntomas sistémicos
Cómo citar
Plaudit
Resumen
El síndrome DRESS (exantema inducido por fármacos con eosinofilia y síntomas sistémicos) es una reacción idiosincrática (tipo B), que se distingue por eosinofilia periférica y síntomas sistémicos, como fiebre, exantema, linfadenopatía, hepatitis, linfocitos atípicos y elevación de enzimas hepáticas al menos dos veces su valor normal o incremento de la alanina aminotransferasa (ALT) >100 U/L. La incidencia es de 1 por cada 1,000 a 10,000 exposiciones y su mortalidad es de 10 a 20%. El tratamiento se basa en esteroides y en la suspensión del fármaco sospechoso. Se comunican los casos de seis pacientes con síndrome DRESS atendidos en el Centro Médico Nacional Siglo XXI, de septiembre de 2012 a septiembre de 2013, que correspondieron a 12.5% de los pacientes atendidos con reacciones adversas a fármacos.
Referencias
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Derechos de autor 2014 Revista Alergia México