Abstract
Background: Allergy skin prick tests are important tools for the diagnosis of respiratory allergic diseases. Cockroach antigens have been identified as the cause of rhinitis, asthma, and other allergic diseases.
Objective: To show that the cockroach antigen participates in the cause of allergic diseases.
Methods: A retrolective and cross-sectional study was carried out, for which clinical records and history of atopy were reviewed; the results were obtained from blood biometry, nasal cytology, total IgE, and coproparasitoscopic serial tests. After prior informed consent, skin tests were applied in 3-74 year-old patients.
Results: 1,837 patients were studied; the prevalence of cutaneous reactivity to the cockroach antigen was of 17.90%; 56% of the patients had a diagnosis of allergic rhinitis, and only 6% had been diagnosed with asthma and rhinitis.
Conclusion: The application of the cockroach antigen in skin tests must be considered in the practice of all allergists.
References
Harrison C. Experimental researches on the causes and nature of Catarrhus Aestivus hay fever or hay asthma. Reino Unido: Bailliere, Tindall & Cox; 1873.
Salazar-Mallén M. Diagnóstico de los padecimientos alérgicos. En: Méndez-Oteo F, editor. La alergia en la teoría y en la práctica. México: Librería de Medicina; 1958.
Bernton H, Brown H. lnsect allergy: preliminay studies of the cockroach. J Allergy. 1964;35:506-513. DOI: 10.1016/0021-8707(64)90082-6
O’Connor GT, Gold DR. Cockroach allergy and asthma in a 30-year-old man. Environ Health Perspect. 1999;107(3):243-247. DOI: 10.1289/ehp.99107243
Kang B, Vellody D, Homburger H, Yunginger JW. Cockroach cause of allergic asthma. Its specificity and immunologic profile. J Allergy Clin Immunol. 1979;63(2):80-86. DOI: 10.1016/0091-6749(79)90196-9
Portnoy J, Chew G, Phipatanakul W, Williams PB, Grimes C, Kennedy K, et al. Environmental assessment and exposure reduction of cockroaches: a practice parameter. J Allergy Clin Immunol. 2013;321(4):802-808. DOI: 10.1016/j.jaci.2013.04.061
Mariño-Pedraza E. Fósiles vivientes: cucarachas. México: Comisión Nacional para el Conocimiento y Uso de la Biodiversidad; 2011. Disponible en: http://bioteca.biodiversidad.gob.mx/janium/Documentos/7259.pdf
O’Hehir R, Stephen H, Sheikh A. Alérgenos y contaminantes de interior y de exterior. En: Middleton. Alergología esencial. España: Elsevier; 2017.
Arruda L, Vailes L, Mann B, et al. Molecular cloning of a major cockroach (Blattella germanica) allergen, Bla g 2 sequence homology to the aspartic proteases. J Biol Chem.1995;270(33):19563-19568. DOI: 10.1074/jbc.270.33.19563
Kwang S, Kyoung J, Chein-Soo H, et al. IgE binding reactivity of peptide fragments of Bla g 4, a major german cockroach allergen. Korean J Parasitol. 2008(2947)31-36. DOI: 10.3347/kjp.2009.47.1.31
Jeong KJ, Jeong KY, Kim CR, Yong TS. IgE-binding epitope analysis of Bla g 5, the German cockroach allergen. Protein Pept Lett. 2010;17(5):573-577. DOI: 10.2174/092986610791112765.
Hindley J, Wünschmann S, Satinover SM, Woodfolk JA, Chew FT, Pomés A, et al. Bla g 6: a troponin C allergen from Blattella germanica with IgE binding calcium dependence. J Allergy Clin Immunol. 2006;117:1389-1395. DOI: 10.1016/j.jaci.2006.02.017
Jeong KY, Hong CS, Yong TS. Allergenic tropomyosins and their cross-reactivities. Protein Pept Lett. 2006;13(8):835-845. DOI: 10.2174/092986606777841244
Do DC, Zhao Y, Gao P. Cockroach allergen exposure and risk of asthma. Allergy. 2016(4):463-474. DOI: 10.1111/all.12827
Kleine-Tebbe J, Hamilton RG, Goodman RE. Cockroach allergens: coping with challenging complexity. J Allergy Clin Immunol. 2019;143(4):1342-13344. DOI: 10.1016/j.jaci.2019.01.028
Shafique R, Inam M, Ismail M, et al. Group 10 allergens (tropomyosins) from house-dust mites may cause covariation of sensitization to allergens from other invertebrates. Allergy Rhinol (Providence). 2012;3(2):e74-e87. DOI: 10.2500/ar.2012.3.0036
Bao-Qing S, Xu-Xin L, Birgitte G, Zhong NS. Prevalence of sensitivity to cockroach allergens and IgE cross-reactivity between cockroach and house dust mite allergens in Chinese patients with allergic rhinitis and asthma. Chin Med J (Engl). 2010;123(24):3540-3544. DOI: 10.3760/cma.j.issn.0366-6999.2010.24.007
Iduñate F, Pérez J, Celio R, et al. Asma e inmunología clínica en pediatría. Segunda edición. México: Compedia; 2019. DOI: 1024245/aaicp.v2id.3110
Lockett GA, Patil VK, Soto-Ramírez N, et al. Epigenomics and allergic disease. Epigenomics. 2013;5(6):685-99. DOI: 10.2217/epi.13.68
Perzanowski MS, Chew GL, Divjan A, Ridder R, Tang D, Diaz D, et al. Early-life cockroach allergen and polycyclic aromatic hydrocarbon exposures predict cockroach sensitization among inner-city children. J Allergy Clin Immunol. 2013;131(3):886-893. DOI: 10.1016/j.jaci.2012.12.666
Pearce N, Aït-Khaled N, Beasley R, Mallol J, Keil U, Mitchell E, et al. Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2007;62(9):758-766. DOI: 10.1136/thx.2006.070169
Pomés A, Mueller GA, Randall TA, Chapman MD, Arruda LK. New insights into cockroach allergens. Curr Allergy Asthma Rep. 2017;17(4):25. DOI: 10.1007/s11882-017-0694-1
Gaffin JM, Phipatanakul W. The role of indoor allergens in the development of asthma. Curr Opin Allergy Clin Immunol. 2009;9(2):128-135. DOI: 10.1097/aci.0b013e32832678b0
McCormack MC, Breysse PN, Hansel NN, Matsui EC, Tonorezos ES, Curtin-Brosnan J, et al. Common household activities are associated with elevated particulate matter concentrations in bedrooms of inner-city Baltimore pre-school children. Environ Res. 2008;106(2):148-155. DOI: 10.1016/j.envres.2007.08.012
Hansel NN, Breysse PN, McCormack MC, Matsui EC, Curtin-Brosnan J, Moore L, et al. A longitudinal study of indoor nitrogen dioxide levels and respiratory symptoms in inner-city children with asthma. Environ Health Perspect. 2008;116(10):1428-1432. DOI: 10.1289/ehp.11349
Olmedo O, Goldestein F, Acosta L, Divjan A, Rundle AG, Chew GL, et al. Neighborhood differences in exposure and sensitization to cockroach, mouse, dust mite, cat and dog allergens in New York City. J Allergy Clin Immunol. 2011;128(2):284-292. DOI: 10.1016/j.jaci.2011.02.044
Baeza-Bacab MA, Dávila-Velázquez JR, Loeza-Medina SR. Prevalencia de pruebas cutáneas positivas a alérgenos intradomiciliarios en preescolares con alergia respiratoria en Mérida, Yucatán, México. Rev Alerg Mex. 2005;52(6):237-242. Disponible en: http://www.scielo.org.mx/pdf/ram/v64n1/2448-9190-ram-64-01-00007.pdf
Bedolla-Barajas M, Morales-Romero J, Hernández-Colín DD, Cruz-David A. Prevalencias de sensibilización a alérgenos más comunes en adultos mayores del Occidente de México. Rev Alerg Mex. 2012;59(3):131-138. Disponible en: https://www.researchgate.net/publication/287557680_Prevalence_of_sensitization_to_common_allergens_in_older_adults_of_western_Mexico
Zazueta ID, Espinoza-Escobar L. Sensibilización alergénica en niños con asma y rinitis alérgica, del Hospital General de Culiacán. Imbiomed. 2010;4(2):49-53. Disponible en: http://hgculiacan.com/revistahgc/archivos/Assin %2014 %20Sensibilizaci %C3 %B3n %20Alerg %C3 %A9nica %20en %20Ni %C3 %B1os %20con %20Asma %20y %20Rinitis %20Al %C3 %A9rgica.pdf
Capriles A, Dockhom R. House dust, mite (Dermatophagoides farinae) and cockroach allergy in a midwestern population. Ann Allergy. 1979;42(3):160-165.
Sánchez-Borges M, Suárez-Chacón R, Capriles-Hulett A, Caballero-Fonseca F, Fernández-Caldas E. Anaphylaxis from ingestion of mites: Pancake anaphylaxis. J Allergy Clin Immunol. 2013;131(1):31-35. DOI: 10.1016/j.jaci.2012.09.026
Sánchez-Borges M, Suárez-Chacón R, Capriles-Hulett A, Caballero-Fonseca F, Fernández-Caldas E. Pancake syndrome (oral mite anaphylaxis). World Allergy Organ J. 2009;2(5):91-96. DOI: 10.1186/1939-4551-2-5-91
Bedolla-Barajas M, Torres-Álvarez NE, Contreras-González U, Hernández-Colín D, Bedolla-Pulido TI, Robles-Figueroa M, et al. Alta prevalencia de sensibilización a alimentos en adultos con enfermedades alérgicas residentes en la zona metropolitana de Guadalajara. Rev Alerg Mex. 2017;67(1):66-75. DOI: 10000-0003-4915-1582
Larenas-Linnemann D, Luna-Pech JA, Rodriguez-Pérez N, Rodríguez-González M, Arias-Cruz A, Costa-Domínguez MC, et al. GUIMIT 2019, Guía Mexicana de Inmunoterapia. Guía de diagnóstico de alergia mediada por IgE e inmunoterapia aplicando el método ADAPTE. Rev Alerg Mex. 2019;66(Supl 1): 1-105. Disponible en: http://revistaalergia.mx/ojs/index.php/ram/article/view/631/1011
Hill DA, Spergel JM. The atopic march: critical evidence and clinical relevance. Ann Allergy Asthma Immunol. 2018;120(2):131-137. DOI: 10.1016/j.anai.2017.10.037
Anon JB, Jacobs MR, Poole MD, Ambrose PG, Benninger MS, Hadley JA, et al. Antimicrobial treatment guidelines for acute bacterial rhinosinusitis. Otolaryngol Head Neck Surg. 2004;130(1 Suppl):1-45. DOI: 10.1016/j.otohns.2003.12.003
Gelber LE, Seltzer LH, Bouzoukis JK, Pollart SM, Chapman MD, Platts-Mills TA. Sensitization and exposure to indoor allergens as risk factors for asthma among patients presenting to hospital. Am Rev Respir Dis. 1993;147(3):573-578. DOI: 10.1164/ajrccm/147.3.573
Rosenstreich DL, Eggleston P, Kattan M, Baker D, Slavin RG, Gergen P, et al. The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. N Engl J Med. 1997;336:1356-1363. DOI: 10.1056/NEJM199705083361904
Eggleston PA, Rosenstreich D, Lynn H, Gergen P, Baker D, Kattan M, et al. Relationship of indoor allergen exposure to skin test sensitivity in inner-city children with asthma. J Allergy Clin Immunol. 1998;102:563-570. DOI: 10.1016/S0091-6749(98)70272-6
Rego F, Giavina-Bianchi P, Kailil, J, Arruda LK, Toledo-Barros M. The hammock: a reservoir of allergens. Clinics (São Paulo). 2011;66(7):1199-1202. DOI: 10.1590/S1807-59322011000700013
Rojas-Méndez IC, Arana-Muñoz O, López-García AI, Rivero-Yeverino D, Caballero-López CG, Papaqui-Tapia S. Frecuencia de reactividad cutánea hacia antígenos inhalables en pacientes en pacientes con cuadro clínico de enfermedad alérgica. Rev Alerg Mex. 2017;64(1):10-11. DOI: 10.29262/ram.v64i1.185
Global Strategy for Asthma Management and Prevention. EE. UU.: Global Initiative for Asthma; 2020.
Mueller GA, Pedersen LC, Glesner J, Edwards LL, Zakzuk J, London RE, et al. Analysis of glutathione S-transferase allergen cross-reactivity in a North American population: relevance for molecular diagnosis. J Allergy Clin Immunol. 2015;136(5):1369-1377. DOI: 10.1016/j.jaci.2015.03.015
Larenas-Linnemann D, Arias-Cruz A, Lou M, del Prado C. Alérgenos usados en las pruebas cutáneas en México. Rev Alerg Mex. 2009;56(2):41-47. Disponible en: https://www.researchgate.net/publication/242541859_Alergenos_usados_en_las_pruebas_cutaneas_en_Mexico
Wallace DV, Dykewicz MS, Bernstein DI, Blessing-Moore J, Cox L, Khan DA, et al. The diagnosis and management of rhinitis: an updated practice parameter. J Allergy Clin Immunol. 2008;122(2):S1-S84. DOI: 10.1016/j.jaci.2008.06.003
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